Genomics of Klebsiella pneumoniae

New paper from the Holt lab out in PNAS: Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health

There have been lots of really nice Klebs genomics papers out in the last 18 months or so, examining the evolution of the ST258 clone that carries the KPC gene (K. pneumoniae carbapaenemase) and is wreaking havoc in hospitals all over the place (including recently in Melbourne), and also several hospital-based studies tracking transmission and evolution of local drug-resistant outbreaks.

But that is just the tip of the K. pneumoniae iceberg. Our paper asks a completely different set of questions, which you could basically sum up as “what the hell is Klebsiella pneumoniae anyway?” …

Read more on the Holt lab website.

Selected media coverage:

• Scientists map Klebsiella pneumoniae superbug’s genome, The Age

New superbug threat on the horizon, ABC News