CfSG seminar – Ashley Farlow – 29th April, 2016


The global evolutionary history of Arabidopsis thaliana
Ashley Farlow, Magnus Nordborg & The 1001 Arabidopsis Genomes Consortium.
Friday 29th April, 2016
ESJ King Theatre, Medical Building, The University of Melbourne
The plant Arabidopsis thaliana serves not only as a model organism for fundamental molecular and cellular processes, but has also greatly advanced our understanding of the origins and consequences of intraspecific genome variation. We have produced a detailed variation map from 1135 high-quality resequenced genomes representing the global population in its native Eurasian and North African range, and in recently colonized North America.
We identified relict populations that continue to inhabit ancestral habitats, primarily in the Iberian Peninsula. They have mixed with a lineage that has spread to northern latitudes from an unknown glacial refugium and is now found in a much broader range of habitats.
I will also discuss the spontaneous mutation rate in the fission yeast Schizosaccharomyces pombe. Specifically, that (1) the mutation rate is robust to environmental change, (2) CpG sites are excessively liable to mutation even in the absence of DNA methylation, and (3) the flocculation pathway plays an atypical role in this yeast species.
Enquiries: Andrew Siebel (