A genome-wide association scan in admixed Latin Americans identiﬁes loci inﬂuencing facial and scalp hair features
Adhikari K, et al., Balding D & Ruiz-Linares A. NATURE COMMUNICATIONS 7:10815
A study published earlier this year (2016) in Nature Communications by the Centre’s Professor David Balding and colleagues disproved the assumption that children are the cause for their parents’ grey hairs. Instead, they found the genes responsible for those grey hairs, along with those linked to bushy eyebrows and patchy beards.
The genome regions associated with hair features are enriched for signals of selection, consistent with proposals regarding the evolution of human hair. See Figure 1.
Figure 1 | GWAS results overview. At the top are shown drawings illustrating the seven hair features examined in the CANDELA study sample. Thick lines connect these features with the candidate genes identiﬁed in regions with SNPs reaching genome-wide signiﬁcant association. At the bottom is shown a composite Manhattan plot displaying all signiﬁcantly associated SNPs for the hair features examined. The rs number of the SNP with the smallest P value is shown at the top of each association peak.
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